''Equid alphaherpesvirus 3'', formerly ''Equine herpesvirus 3'' (EHV-3), is a

virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsk ...

of the family ''

Herpesviridae ''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπει� ...

'' that affects

horse The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million yea ...

Pathology

It causes a disease known as equine coital exanthema. The

disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...

is spread through direct and sexual contact, contaminated handlers and equipment, and possibly through flies carrying infected

vaginal discharge Vaginal discharge is a mixture of liquid, cells, and bacteria that lubricate and protect the vagina. This mixture is constantly produced by the cells of the vagina and cervix, and it exits the body through the vaginal opening. The composition, amou ...

. EHV-3 has an

incubation period Incubation period (also known as the latent period or latency period) is the time elapsed between exposure to a pathogenic organism, a chemical, or radiation, and when symptoms and signs are first apparent. In a typical infectious disease, the in ...

of as little as two days. Signs of the disease include often painful

pustule A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ...

s and ulcerations of the

vagina In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...

penis A penis (plural ''penises'' or ''penes'' () is the primary sexual organ that male animals use to inseminate females (or hermaphrodites) during copulation. Such organs occur in many animals, both vertebrate and invertebrate, but males d ...

prepuce Prepuce , or as an adjective, preputial , refers to two homologous structures of male and female genitals: *Clitoral hood, skin surrounding and protecting the head of the clitoris *Foreskin, skin surrounding and protecting the head of the penis in ...

, and

perineum The perineum in humans is the space between the anus and scrotum in the male, or between the anus and the vulva in the female. The perineum is the region of the body between the pubic symphysis (pubic arch) and the coccyx (tail bone), includi ...

. Lesions may also be seen on the lips and

teat A teat is the projection from the mammary glands of mammals from which milk flows or is ejected for the purpose of feeding young. In many mammals the teat projects from the udder. The number of teats varies by mammalian species and often corr ...

s. Usually the only symptom seen is a decreased

libido Libido (; colloquial: sex drive) is a person's overall sexual drive or desire for sexual activity. Libido is influenced by biological, psychological, and social factors. Biologically, the sex hormones and associated neurotransmitters that act u ...

in stallions. The lesions heal within two weeks. As with other herpes viruses, the virus remains latent in the host for life. Carrier animals can sometimes be identified by spots of pigment loss on dark skin in the genital region. EHV-3 is best prevented by taking note of present clinical signs and keeping infected horses isolated and breeding stock from sexual contact with other horses. Keep the wounds clean by rinsing with clean water or saline. Antibiotic ointments should not be used on the lesions, because they are caused by a virus, and viruses are not sensitive to antibiotics. Rinsing is enough to keep the numbers of bacteria down. It is important to always maintain good hand hygiene before and after touching the genital area in all horses, and clean instruments, as the virus can be spread by contaminated hands or equipment. Disinfect equipment and stalls that has been used for horses with clinical signs.

References

Horse diseases Varicelloviruses Animal viral diseases {{Veterinary-med-stub